SEARCH

CONTACT

email: lich@vscht.cz address:
ICT Prague
Technická 5
166 28 Prague 6
map: how to find us

ICT Prague

Logo VŠCHT

Facebook

Facebook

Bioinformatika

Bioinformatika

ENBIK

ENBIK

« one step back EDUCATION

Essential Bioinformatics (N143030SIS)

Lecture Exercise Laboratory Examination Credits
2 2 0 Z+Zk 5
   
Guarantor Svozil Daniel
Teacher Svozil Daniel

Annotation:

The course introduces students to bioinformatics, which uses computer databases to store, retrieve and assist in understanding biological information. Genome-scale sequencing projects have led to an explosion of genetic sequences available for automated analysis. These gene sequences are the codes, which direct the production of proteins that in turn regulate all life processes. Students will be introduced to the basic concepts behind bioinformatics and computational biology tools. Hands-on sessions will familiarize students with the details and use of the most commonly used online tools and resources.

Syllabus:

  1. Biological preliminaries I - Central dogma of molecular biology, introduction to cell biology - mitosis and meiosis
  2. Biological preliminaries II - Classical genetics, introduction to evolution
  3. Introduction to genomics, genome sequencing
  4. Sequence alignment I - Pairwise alignment, sequence database searching (BLAST)
  5. Sequence alignment II - Multiple sequence alignment, profiles, hidden Markov models
  6. Genome characteristics I - Gene detection, genome annotation
  7. Genome characteristics II - Prediction of promoters and regulatory elements
  8. Evolutionary processes - Phylogenetic trees
  9. Structural bioinformatics I - Structure of DNA, RNA and proteins
  10. Structural bioinformatics II - Protein structure prediction
  11. Structural bioinformatics III - Nucleic acids structure prediction
  12. Gene expression analysis
  13. DNA forensic analysis

Notes:

  • Credit: practical project
  • Exam: written test